. Kalmbach and Michael D . Mauk response Multiple sites of extinction for a single learned
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Multiple sites of extinction for a single learned response.
Most learned responses can be diminished by extinction, a process that can be engaged when a conditioned stimulus (CS) is presented but not reinforced. We present evidence that plasticity in at least two brain regions can mediate extinction of responses produced by trace eyelid conditioning, where the CS and the reinforcing stimulus are separated by a stimulus-free interval. We observed individ...
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1 1 2 3 4 Title: Cerebellar cortex contributions to the expression and timing of 5 conditioned eyelid responses. 6 7 Abbreviated title: Cerebellar cortex and eyelid conditioning 8 9 Authors: Brian E. Kalmbach, Tobin Davis, Tatsuya Ohyama, Frank Riusech, 10 William L. Nores and Michael D. Mauk 11 Center for Learning and Memory 12 Section of Neurobiology 13 University of Texas Austin 14 1 Univers...
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Like many forms of Pavlovian conditioning, eyelid conditioning displays robust extinction. We used a computer simulation of the cerebellum as a tool to consider the widely accepted view that extinction involves new, inhibitory learning rather than unlearning of acquisition. Previously, this simulation suggested basic mechanistic features of extinction and savings in eyelid conditioning, with pr...
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We test the hypothesis that the cerebellar cortex is required for the extinction of conditioned eyelid responses in rabbits trained using standard Pavlovian delay procedures. Following 10 daily training sessions during which rabbits achieved asymptotic performance, lesions of the ipsilateral hemisphere of the cerebellar cortex were made by aspiration. The target of these lesions was the anterio...
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